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Stephen L. Buka, Sc.D.

  • Professor and Chair of Epidemiology, Brown University
  • Director of the Center for Population Health & Clinical Epidemiology, Public Health Program, Brown University
  • Director of the Center for the Study of Human Development, Brown University

Dr. Stephen Buka - Send email to stephen_buka@brown.edu

Stephen L. Buka, Sc.D., was at Harvard School of Public Health (HSPH) for 20 years in the Departments of Maternal Child Health and Epidemiology, and currently holds an appointment as an Adjunct Professor of Epidemiology at HSPH. He is Professor and Chair of Epidemiology at Brown University, and also directs Brown’s Center for Population Health and Clinical Epidemiology and the Center for the Study of Human Development.  Dr. Buka is an expert in the measurement of the key obstetric events and their effect on adult neuropsychiatric conditions and in childhood. As director of the follow-up of the NE CPP, which he has followed for over 30 years, he has expertise in the baseline biological and clinical measures during pregnancy, delivery and early life.  He is the custodian of newly collected biological samples, has expertise in location and recruitment of the NE CPP, and maintains the connection to the central NCPP database; all of which will be critical to the success of SCOR Project 1.  Dr. Buka is also the PI of the Providence, RI and Bristol County, MA sites of the National Children’s Study, a new prenatal cohort with many similarities to the CPP which aims to study 100,000 children across the United States, following them from before birth until age 21.  He has worked with Dr. Goldstein for over 15 years.

Representative Publications:

Buka SL, Tsuang MT and Lipsitt LP. Pregnancy/delivery complications and psychiatric diagnosis. A prospective study. Archives General Psychiatry 1993; 50(2): 151-156.

Buka SL, Lipsitt LP. Towards a developmental epidemiology. In: Friedman SL, Haywood HC (eds.) Developmental follow-up: Concepts, domains and methods. Academic Press 1994; 331-350.

Klebanof MA, Zemel BS, Buka SL, Zierler S. Long term follow-up of participants in the Collaborative Perinatal Project subjects. Pediatric and Perinatal Epidemiology 1998;12(3):334-346.

Buka SL, Goldstein JM, Seidman LJ, Zornberg G, Donatelli JA, Denny LR, Tsuang MT. Prenatal complications, genetic vulnerability, and schizophrenia: The New England Longitudinal Studies of Schizophrenia. Psychiatric Annals 1999; 29(3): 151-156.

Tomeo CA, Rich-Edwards JW, Michels KB, Berkey CS, Hunter DJ, Frazier AL, Willett WC, Buka SL. Reproducibility and validity of maternal recall of pregnancy related events. Epidemiology 1999; 10(6): 774-777.

Buka SL
, Tsuang MT, Torrey EF, Klebanof MA, Bernstein D, Yolken RH. Maternal infections and subsequent psychosis among offspring: A 40-year prospective study. Archives General Psychiatry 2001; 58(11): 1032-1037.

Buka SL
, Tsuang, MT, Torrey, EF, Klebanoff, MA, Wagner, RL, Yolken, RH. Maternal cytokine levels during pregnancy and adult psychosis. Brain, Behavior, and Immunity 2001; 15(4): 411-420.

Buka SL
, Brennan RT, Rich-Edwards JW, Raudenbush SW, Earls FJ. Neighborhood support and the birth weight of urban infants. American Journal of Epidemiology 2003; 157(1): 1-8.

Buka SL
, Shenassa ED, Niaura R. Elevated risk of tobacco dependence among offspring of mothers who smoke during pregnancy: A 30-year prospective study. American Journal of Psychiatry 2003 160(11): 1978-1984.

Buka SL
, Goldstein JM, Spartos E, Tsuang MT. The retrospective measurement of prenatal and perinatal events: Accuracy of maternal recall:. Schizophrenia Research 2004; 71: 417-426.

Stroud LR, Solomon C, Shenassa ED, Papandonatos G, Niaura R, Lipsitt LP, Buka SL.  Long-term stability of maternal prenatal steroid hormones from the National Collaborative Perinatal Project: Still valid after all these years.  Psychoneuroendocrinology, 2007, Jan 30.

Cerda M, Rich-Edwards J, Buka SL. Neighborhood influences on the association between maternal age and birth weight: A multilevel investigation of age-related disparities in health. Social Science Medicine 2008 March; 66(9); 2048-2060.

Buka SL
, Cannon TD, Torrey EF, Yolken RH. Maternal exposure to Herpes Simplex Virus and risk of psychosis among adult offspring.  Biological Psychiatry. 2008 April; 63(8); 809-815. PMID: 17981263

Vasiliadis HM, Gilman SE, Buka SL. Fetal growth restriction and the development of major depression. Acta Psychiatrica Scandinavica. 2008 April; 117 (4); 306-312. PMID: 1832135

Palmsten K, Buka SL, Michels KB. Maternal pregnancy-related hypertension and risk for hypertension in offspring later in life. Obstet Gynecol. 2010 Oct;116(4):858-64.

Donatelli JA, Seidman LJ, Goldstein JM, Tsuang MT, Buka SL.  Children of parents with affective and nonaffective psychoses: a longitudinal study of behavior problems. Am J Psychiatry. 2010 Nov;167(11):1331-8.

Wen X, Triche EW, Hogan JW, Shenassa ED, Buka SL. Birth weight and adult hypercholesterolemia: subgroups of small-for-gestational-age based on maternal smoking status during pregnancy. Epidemiology. 2010 Nov;21(6):786-90.

Vasiliadis HM, Buka SL, Martin LT, Gilman SE. Fetal growth and the lifetime risk of generalized anxiety disorder. Depress Anxiety. 2010 Nov;27(11):1066-72. doi: 10.1002/da.20739.

Ball SW, Gilman SE, Mick E, Fitzmaurice G, Ganz ML, Seidman LJ, Buka SL. Revisiting the association between maternal smoking during pregnancy and ADHD. J Psychiatr Res. 2010 Nov;44(15):1058-62.

Wen X, Triche EW, Hogan JW, Shenassa ED, Buka SL. Association between placental morphology and childhood systolic blood pressure. Hypertension. 2011 Jan;57(1):48-55. Epub 2010 Nov 15.

Goldstein JM, Cherkerzian S, Seidman LJ, Petryshen TL, Fitzmaurice G, Tsuang MT, Buka SL. Sex-specific rates of transmission of psychosis in the New England high-risk family study. Schizophr Res. 2011 Feb 17.

Publications by Dr. Buka